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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
23.33
Human Site:
Y36
Identified Species:
34.22
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
Y36
C
A
V
L
V
K
E
Y
V
E
S
E
N
G
Q
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
Y36
C
A
V
L
V
K
E
Y
V
E
S
E
N
G
Q
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
L499
R
V
G
R
S
W
A
L
P
H
P
Q
R
G
K
Dog
Lupus familis
XP_849292
706
81555
Y36
C
A
V
L
V
K
E
Y
V
E
S
E
N
G
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
Y36
C
A
V
L
V
K
E
Y
V
E
S
E
N
G
Q
Rat
Rattus norvegicus
Q9WTQ0
707
81732
Y36
C
A
V
L
V
K
E
Y
V
E
S
E
N
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
S36
C
A
V
L
V
K
E
S
I
E
S
E
N
G
Q
Chicken
Gallus gallus
NP_001006133
699
80179
L36
A
I
K
M
K
E
A
L
T
T
E
R
G
K
T
Frog
Xenopus laevis
Q7LZQ8
671
76506
A38
V
K
E
H
K
F
T
A
R
F
F
K
Q
P
T
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
P46
I
A
R
F
F
K
Q
P
T
F
C
S
H
C
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
V38
D
K
A
K
A
E
A
V
V
E
H
T
V
A
V
Honey Bee
Apis mellifera
XP_394743
624
71014
Y38
T
H
V
S
S
E
G
Y
T
Y
R
T
R
I
P
Nematode Worm
Caenorhab. elegans
P34722
704
80280
K40
P
A
V
N
V
K
E
K
I
E
V
N
G
E
S
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
E36
Q
L
R
C
F
P
E
E
G
G
G
G
D
P
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
K172
Y
R
I
Q
M
L
N
K
A
L
K
K
Y
Q
A
Red Bread Mold
Neurospora crassa
P87253
1142
127954
R45
S
K
L
D
T
Q
M
R
E
G
R
R
N
L
E
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
86.6
0
0
13.3
N.A.
13.3
13.3
40
6.6
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
93.3
13.3
6.6
26.6
N.A.
20
20
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
50
7
0
7
0
19
7
7
0
0
0
0
7
7
% A
% Cys:
38
0
0
7
0
0
0
0
0
0
7
0
0
7
0
% C
% Asp:
7
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
0
0
7
0
0
19
50
7
7
50
7
38
0
7
7
% E
% Phe:
0
0
0
7
13
7
0
0
0
13
7
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
7
0
7
13
7
7
13
44
0
% G
% His:
0
7
0
7
0
0
0
0
0
7
7
0
7
0
0
% H
% Ile:
7
7
7
0
0
0
0
0
13
0
0
0
0
7
0
% I
% Lys:
0
19
7
7
13
50
0
13
0
0
7
13
0
7
7
% K
% Leu:
0
7
7
38
0
7
0
13
0
7
0
0
0
7
0
% L
% Met:
0
0
0
7
7
0
7
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
7
0
0
7
0
0
0
0
7
44
0
0
% N
% Pro:
7
0
0
0
0
7
0
7
7
0
7
0
0
13
7
% P
% Gln:
7
0
0
7
0
7
7
0
0
0
0
7
7
7
38
% Q
% Arg:
7
7
13
7
0
0
0
7
7
0
13
13
13
0
0
% R
% Ser:
7
0
0
7
13
0
0
7
0
0
38
7
0
0
7
% S
% Thr:
7
0
0
0
7
0
7
0
19
7
0
13
0
0
19
% T
% Val:
7
7
50
0
44
0
0
7
38
0
7
0
7
0
7
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
38
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _